Disease: Intellectual Disability
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZNF292 O60281 zinc finger protein 292 Enzyme 1.00 0.695 0.423
ZMYND11 Q15326 zinc finger MYND-type containing 11 1.00 0.647 0.500
VIP P01282 vasoactive intestinal peptide Signaling 4.2E-04 0.437 0.846
TRRAP Q9Y4A5 transformation/transcription domain associated protein 1.00 0.572 0.692
TCN2 P20062 transcobalamin 2 1.0E-06 0.578 0.615
SYNGAP1 Q96PV0 synaptic Ras GTPase activating protein 1 Enzyme modulator 1.00 0.584 0.577
SLC6A8 P48029 solute carrier family 6 member 8 Transporter 1.00 0.476 0.846
SHANK3 Q9BYB0 SH3 and multiple ankyrin repeat domains 3 1.00 0.550 0.731
SHANK2 Q9UPX8 SH3 and multiple ankyrin repeat domains 2 8.4E-07 0.663 0.385
SCAMP5 Q8TAC9 secretory carrier membrane protein 5 Enzyme 0.65 0.839 0.192
RORA P35398 RAR related orphan receptor A Nuclear receptor 0.40 0.533 0.808
RAB39B Q96DA2 RAB39B, member RAS oncogene family 0.83 0.619 0.615
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTCHD1 Q96NR3 patched domain containing 1 Receptor 0.98 0.678 0.385
PAX6 P26367 paired box 6 1.00 0.450 0.769
NTF4 P34130 neurotrophin 4 Signaling 1.2E-02 0.644 0.692
NSD1 Q96L73 nuclear receptor binding SET domain protein 1 Epigenetic regulator 1.00 0.505 0.769
NRXN2 P58401 Q9P2S2 neurexin 2 1.00 0.769 0.308
NRXN1 P58400 Q9ULB1 neurexin 1 1.00 0.581 0.692
NR4A2 P43354 nuclear receptor subfamily 4 group A member 2 Nuclear receptor 1.00 0.529 0.846
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
NBEA Q8NFP9 neurobeachin 1.00 0.760 0.538
MTF1 Q14872 metal regulatory transcription factor 1 Transcription factor 0.97 0.751 0.500
MEF2C Q06413 myocyte enhancer factor 2C Transcription factor 1.7E-02 0.517 0.769
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846